ABSTRACT
The government's policies in dealing with the Covid-19 pandemic in the new normal era have a better impact on all sectors of life. In the tourism sector, this policy has an impact on increasing the income of service actors. The same thing also happened to the kelotok tour service provider of Siring Piere Tendean Floating Market, Banjarmasin. However, the increase is still not as significant as before the pandemic. Therefore, they need a livelihood strategy at the beginning of the new normal era of Covid-19. This study aims to analyze the livelihood strategy of the Siring Piere Tendean kelotok tourism service provider in Banjarmasin in the new normal era of Covid-19. The method used in this study was descriptive quantitative with 51 respondents from kelotok service providers. Data sources come from observations, questionnaires, interviews, and documentation. The results showed that the livelihood strategy of the kelotok tour service provider of Siring Piere Tendean during the new normal period of Covid-19 that was most widely carried out was the survival strategy as the main strategy. Meanwhile, the innovation carried out is to apply other strategies, such as diversification strategies;consolidation strategies;accumulation strategies: and network strategies.
ABSTRACT
BACKGROUND: Miliary tuberculosis is a life-threatening disease caused by the hematogenous spread of Mycobacterium tuberculosis. It is uncommon in pregnancy. Mortality rates for patients with miliary tuberculosis who require mechanical ventilation are high (60-70%). CASE PRESENTATION: We reported a rare and challenging case, a 35-year-old Asian woman with 34 weeks of pregnancy, and miliary tuberculosis with acute respiratory distress syndrome and septic shock. The patient presented with severe acute respiratory distress syndrome, necessitating mechanical ventilation, vasopressor, and pregnancy termination with caesarean section. The patient underwent blood purification with continuous veno-venous hemofiltration using an oXiris filter for 24 hours. After continuous veno-venous hemofiltration, the patient's condition was greatly improved, and the patient was successfully extubated and was able to breathe spontaneously without vasopressor on the third day. High levels of interleukin-6, interleukin-10, procalcitonin, C-reactive protein, interferon-γ, and tumor necrosis factor-α were found postoperatively. CONCLUSION: The bacterial infection of tuberculosis, acute respiratory distress syndrome, and the stress response from the caesarean section contributed to the high levels of cytokines, which correlated with the patient's severe inflammatory condition. The cytokine levels were greatly reduced after the blood purification procedure and this might be associated with the patient's clinical improvement. Extracorporeal blood purification could help to disrupt the vicious cycle of inflammation.
Subject(s)
Mycobacterium tuberculosis , Respiratory Distress Syndrome , Shock, Septic , Tuberculosis, Miliary , Humans , Pregnancy , Female , Adult , Tuberculosis, Miliary/complications , Cesarean Section/adverse effects , Respiratory Distress Syndrome/etiology , Shock, Septic/complicationsABSTRACT
COVID-19 can be spread through the air, caused by inhaling smaller droplets1 containing SARS-CoV-2 in an indoor environment. In particular, both people with symptoms and people without symptoms make many small droplets and respiratory droplets when they breathe, sneeze, cough, or speak. When these tiny droplets are exposed to the air around them, they can react with the particles (PM) and stay in the air for a long time. The survival period depends on various conditions, including the type of surface, temperature, and relative humidity. The ventilation system is one way to solve this problem. This research makes a significant contribution to the development of intelligent ventilation systems utilizing the Internet of Things (IoT) and decision tree algorithms. The function of this system is to get a clean room environment from viruses by spraying disinfectant automatically and controlling the temperature and humidity of the air. Based on the results of this study, the system is able to control and categorize room conditions based on temperature and humidity factors. The classification value using the C4.5 decision tree algorithm is 92.33% with an average temperature and humidity value of 25oC and 49%. © 2022 IEEE.
ABSTRACT
Inflammatory response in COVID-19 contributes greatly to disease severity. Mesenchymal Stem Cells (MSCs) have the potential to alleviate inflammation and reduce mortality and length of stay in COVID-19 patients. We investigated the safety and effectiveness of normoxic-allogenic umbilical cord (NA-UC)-MSCs as an adjunctive treatment in severe COVID-19 patients. A double-blind, multicentric, randomized, placebo-controlled trial involving severe COVID-19 patients was performed from January–June 2021 in three major hospitals across Java, Indonesia. Eligible participants (n = 42) were randomly assigned to two groups (1:1), namely the intervention (n = 21) and control (n = 21) groups. Either NA-UC-MSCs or NaCl placebo were administered daily. The primary outcome was the duration of hospitalization. Meanwhile, the secondary outcomes were radiographical progression (Brixia score), respiratory and oxygenation parameters, and inflammatory markers, in addition to the safety profile of NA-UC-MSCs. NA-UC-MSC administration did not affect the length of hospital stay of severe COVID-19 patients, nor did it improve the Brixia score or mMRC dyspnoea scale better than placebo. Nevertheless, NA-UC-MSCs led to a better recuperation in oxygenation index (120.80 ± 72.70 baseline vs 309.63 ± 319.30 D + 22, p = 0.038) and oxygen saturation (97.24 ± 4.10% vs 96.19 ± 3.75% in placebo, p = 0.028). Additionally, compared to the placebo group, the treatment group had a significantly smaller increase in PCT level at D + 22 (1.43 vs. 12.76, p = 0.011). No adverse effects, including serious ones, were recorded until D + 91. NA-UC-MSC therapy is a very safe adjunct for COVID-19 patients. It improves the oxygenation profile and carries potential to suppress inflammation.
Subject(s)
COVID-19 , InflammationABSTRACT
The study tested the preceding research model to develop theories regarding aspects of authentic leadership and employee coping in public organizations. Researchers conducted a survey on public organizations with 198 respondents whose task is providing services to the community. Researchers used the convenience sampling technique to take samples of respondents who work in public organizations in Bandung, Indonesia. To test the proposed research model, researchers used a non-parametric approach to predict the model of research. The result of this study indicates there is a connection between authentic leadership and psychological vulnerability mediated by proactive coping in uncertain situations, especially during COVID- 19. The study result contributes to filling the research gaps, which shows the effectiveness of authentic leadership in encouraging proactive behavior of employees in dealing with stress and reducing the impact of psychological vulnerability on employees of public organizations. The research implication recommends that leaders of public organizations encourage the employees' proactive behavior by providing direct support. Thus, the employees can be more effective in dealing with uncertain situations to decrease the impact of psychological vulnerability. © 2022 Hadian et al.
ABSTRACT
During the COVID-19 Pandemic, there were changes in work patterns such as work from home. The impact of the change in work from home patterns needs to be of concern to the organization. Working conditions that are not conducive to overcoming these changes in work patterns can lead to deviance in employee behavior due to mental health. This study investigates the effect of working conditions on the quality of life of employees. The research method used a survey approach with non-parametric analysis techniques. It is testing using a sample of 201 employees of respondents with a simple random sampling technique in local governments that handle transportation problems in West Bandung regency. The results indicated a significant influence of the work environment on the quality of life of employees. This result indicates that the presence of a work environment that is less conducive has a significant impact on the quality of life of employees, as indicated by the presence of anxiety and depression. The research implication shows that it is necessary to minimize existing work-related mental health by managing an efficient work environment. © by the authors.
ABSTRACT
For the time being, COVID-19 has been endemic and presents a varied neurological picture. Moreover, one of the remarkable neurological pictures is posterior reversible encephalopathy. It is a neurotoxic state which is considered a rare manifestation; however, it is essential to recognize. It originates from the disturbance of the blood-brain barrier which causes vasogenic edema and most commonly occurred in the parieto-occipital regions. Thus, we presented a case of a patient diagnosed with COVID-19 infection with posterior reversible encephalopathy syndrome (PRES) as shown at the brain MRI examination. It was categorized as a form of brain disorder in COVID-19.
ABSTRACT
A significant amount of research suggests the common reasons students leave an engineering major include lack of faculty mentoring, lack of a sense of belonging, financial hardships, and course difficulties in the prerequisite STEM courses [1]. Project-based learning (PBL) potentially addresses several of these reasons and increases the chances of a student completing an engineering major. Engineering students are more likely to persist when they feel a sense of belonging and community engagement, when they have early interactions with faculty mentors, and when they experience a series of successes [2]. The research question involves whether student research projects with small, faculty-mentored groups promotes student retention. Students participating in Contra Costa College's Center for Science Excellence (CSE) STEM mentoring program are encouraged to apply for external internships and internal research projects. As of the last cycle before the interruption of internship opportunities associated with COVID-19, 79% of participating students intended to apply for summer internships. Students are also able to work on internal research projects mentored by CSE faculty mentors. Over the past three years, engineering students that have participated in research projects have remained in our program and transferred at a high rate. Of thirty student research participants, fourteen have transferred into engineering majors (47%), two have transferred into other STEM majors (7%), eleven continue to take transfer preparatory courses at Contra Costa College (37%), and the educational status of three students is unknown (10%). For the college as a whole, the transfer rate is 32%, the graduation rate is 24%, and the retention rate after one year is 67%. © American Society for Engineering Education, 2021
ABSTRACT
BACKGROUND: Transferring critically ill patients with COVID-19 is a challenging task; therefore, well-trained medical team is needed. This study aimed to determine the role of in situ simulation training during pandemic by using high-fidelity manikin to improve interprofessional communication, skills and teamwork in transferring critically ill patients with COVID-19. METHODS: This single-blinded randomised control trial included 40 subjects allocated into standard low-fidelity simulator (LFS) and high-fidelity simulator (HFS) groups. Subjects, who were not members of multiprofessional team taking care of patients with COVID-19, in each group were assigned into small groups and joined an online interactive lecture session, two sessions of in-situ simulation and a debriefing session with strict health protocols. The first simulation aimed to teach participants the skills and steps needed. The second simulation aimed to assess transfer skills, communication and teamwork performance, that participants had learnt using a validated, comprehensive assessment tool. Data were analysed using unpaired t test or Mann-Whitney test. RESULTS: The HFS group showed significantly better overall transfer and communication skills than LFS group (89.70±4.65 vs 77.19±3.6, <0.05 and 100 vs 88.34 (63.33-100), p=0.022, respectively). The HFS group also demonstrated significantly better teamwork performance than the standard LFS group (90 (80-900) vs 80 (70-90), p=0.028). CONCLUSION: In situ simulation training using HFS significantly showed better performance than the standard training using LFS in regards to overall transfer and communication skills as well as teamwork performance. The training using HFS may provide a valuable adjunct to improve interprofessional skills, communication and teamwork performance in transferring critically ill patients with COVID-19.Trial registration numberNCT05113823.
Subject(s)
COVID-19 , Simulation Training , Clinical Competence , Critical Illness/therapy , Humans , Interprofessional Relations , Patient Care Team , Prospective StudiesABSTRACT
During the COVID-19 pandemic, medical students might be vulnerable to excessive screen time exposure to cope with distance learning-induced distress. This study aimed to evaluate the distress and screen time before and after distance learning was initiated. Data were collected from 215 subjects. Statistical significance was accepted at p<0.05. The prevalence of distress among medical students was 25.61% and 27.06% before and after distance learning was executed, respectively. Academic-related stressor (ARS) was reported by 49.28% and 63.29% of students during the first and second surveys. The proportion of students with daily screen time ≥7 hours was 51.21% and 63.77% for the first and second surveys, respectively. ARS, interpersonal and intrapersonal-related stressor (IRS), social-related stressor (SRS), and average daily screen time significantly rose in 3-month-time (p<0.0001, p=0.0014, p=0.0261, p=0.0022). There was a significant association between distress and screen time (p=0.0313). ARS was the leading cause of distress. The majority of respondents had a daily screen time ≥7 hours. Both distress and screen time levels significantly increased as distance learning kept progressing. Keywords: COVID-19;distance learning;mental distress;medical students;screen time.
ABSTRACT
Background: This review determined the effect of prone positioning in changes of partial pressure of arterial oxygen/fraction of inspired oxygen (PaO 2 /FiO 2 ) ratio, partial pressure of carbon dioxide (PaCO 2 ), mortality rate, ICU length of stay and duration of mechanical ventilation in intubated COVID-19 patients with severe ARDS. Methods: A computer-aided comprehensive electronic bibliographic search from MEDLINE, EMBASE, and Science Direct were conducted. The search comprised the articles written in English and intubated adults (≥ 18 years old) patients with COVID-19. The primary outcome was comparing PaO 2 /FiO 2 ratio between prone and supine position group. Secondary outcomes were PaCO 2 , ICU discharge, and mortality rate. Review Manager version 5.4 (The Cochrane Collaboration) was used for statistical analyses of the included studies. Results: A total of 7 articles were determined to be eligible, consisting of 1403 intubated COVID-19 patients with ARDS that showed prone position was associated with a higher PaO 2 /FiO 2 ratio compared to supine position (MD 60.17, 95% CI 46.86 - 73.47; p < 0.00001). Four studies reported the PaCO 2 measurement and showed no significant difference between prone and supine position (MD 2.07, 95% CI -2.79 - 6.92; p <0.40). Only two studies reported mortalities, one study had 262 deaths out of 648 patients (40.4%) and one study lost 11 out of 20 patients (55%). One study reported median ICU stay and mechanical ventilation duration (16 days) were significantly longer in prone position group. Conclusion: This meta-analysis showed that prone position improved PaO 2 /FiO 2 ratio in intubated COVID-19 patients with ARDS.
Subject(s)
COVID-19ABSTRACT
The COVID-19 virus appeared at the end of 2019 which was first discovered in Wuhan, China. This virus is widespread in 2020 throughout the world, including Indonesia. South Kalimantan Province cannot be separated from the spread of this virus due to high population mobility, so PSBB is needed with the aim of inhibiting the spread of the virus. Analysis of the potential for implementing PSBB in South Kalimantan Province is needed to determine the level of success that has been implemented. The research objective was to analyze public perceptions regarding the implementation of PSBB in South Kalimantan Province. The research method used quantitative descriptive which was carried out through the online questionnaire Survey123, conducted on July 21, 2020 to August 10, 2020. Based on the research results, the majority of the people of South Kalimantan Province agreed with the existence of the PSBB, but the level of community compliance with government recommendations was still low. The solutions that can be provided include forming an epidemiological team, testing or evaluating the implementation of the PSBB on social and economic aspects, and the need for socialization to the public regarding the importance of government recommendations regarding policies to stop the spread of COVID-19.
ABSTRACT
The Ministry of Health of Indonesia has established large-scale social restrictions (LSSR) to limit the transmission of Covid-19, which inherently causes an increase in screen time levels and the physical activity level of students. This study aims to compare the level of screen time and physical activity before and during LSSR. This cross-sectional study was involved 206 medical students of the Atma Jaya School of Medicine and Health Sciences. Data were collected using a questionnaire and the International Physical Activity Questionnaire (IPAQ) - long form. A paired t-test, Wilcoxon signed-rank test, and McNemar test were used to compare the level of screen time and physical activity before and during LSSR. The mean screen time, sedentary time on weekday and weekend were significantly increased (Δ0.6, Δ1.7, Δ1.3 hours, respectively, all p<0.001), while total calorie of physical activity reduced (Δ-435, p<0.001). The number of students with higher screen time and sedentary time was also raised (Δ12.1%, Δ19.4%, Δ14.6%, respectively, all p<0.001), while the number of students with sufficient physical activity was significantly diminished (Δ-13.6%, p<0.001). There was a shift in the use of application types. The most significant change was Line usage, which had decreased by almost half (from 80 to 43). The pandemic situation greatly affected the students' physical activity behaviour to be more sedentary and changed the use of application type. © 2021 Montenegrin Sports Academy. All rights reserved.
ABSTRACT
Public Libraries (PLs) continue to contribute a great deal to user education in local communities. This paper analyzes the importance of PLs in driving community literacy through promotion of user education for the progressive improvement of the society. The paper stresses the relevance and value of PLs by reassessing the benefits they accrue by analyzing the impact of PLs on community and social education. As indigenous knowledge repositories, PLs play a significant role as community information service providers by driving community literacy. The goal of this paper is to analyze the role played by PLs in driving community education and promoting information literacy in the society. PLs, being storehouses of knowledge, support user education by undertaking active part in community information services. The model helps in explaining and analyzing the efficiency of information search and retrieval process in PLs and how it affects user education and community literacy. The paper also discusses the relevance and value of PLs in this age of digital technology. The findings reinforce the claim that PLs are relevant even in this digital age, and they indeed support user education for the progressive improvement of the society.
ABSTRACT
The goal of this paper is to design a putative transmutable sequence from the oligopeptides derived from the spike protein coding sequence of SARS-COV-2. The purpose for such a sequence is that, the sequence must be unique and be capable of identifying and predicting mutations within the coronavirus genome. By designing a Spike-protein site-specific probe, a novel delivery vehicle could be developed to deliver molecules which would disrupt the structure of the sequence at multiple locations. The autotransmutable sequence can be employed as a vehicle for delivery of Spike protein specific RNA interference molecules that would disrupt and induce strand breakage at different sites of the sequence rendering it non-functional. By applying the knowledge from prior and ongoing research on SARS-COV-2 strains, we attempt to design such a putative novel therapeutic manoeuvre that could act as a vaccine molecule.